• Cdk2/Cyclin Inhibitory Peptide I structure br Methods br Res

  2019-06-27

  

  Methods Results Discussion Conclusions Conflict of interest statement Introduction Pulmonary vein (PV) isolation using a conventional electrode catheter is an effective therapy for atrial fibrillation (AF) [1,2]. However, it requires a long procedure time and has occasionally been

• Common and rare SCN A variants may contribute

  2019-06-27

  

  Common and rare SCN10A variants may contribute to AF susceptibility [59,60]. SCN10A mutations (R14L and R1268Q) cause a loss of function of Nav1.5 current, which is expected to reduce excitability and lead to the development of the arrhythmogenic substrate responsible for BrS and AF. A common varian

• The outcome of sinus node modification with radiofrequency a

  2019-06-27

  

  The outcome of sinus node modification with radiofrequency ablation has been reported, but it involves a high invasive risk associated with the ablation. Thus, careful confirmation of the earliest activation site and ablation of that site is important [2,3]. The clinical use of the 3D-mapping system

• Sor Juana cuyo genio era para Vigil

  2019-06-27

  

  Sor Juana, cuyo genio era para Vigil indudablemente “antimonacal” —recordemos que estamos en pleno periodo posterior AST 487 las leyes de desamortización de los bienes eclesiásticos— tuvo que tomar una decisión “dictada por las exigencias de su sociedad”, por ello, continúa Vigil, si hubiese nacido

• OS is Executive Director of the INDEPTH

  2019-06-27

  

  OS is Executive Director of the INDEPTH Network. PB is Director of the WHO Collaborating Centre for Verbal Autopsy and chairs the Scientific Advisory Committee of the INDEPTH Network. The INDEPTH Network is grateful for core funding from Sida, the Wellcome Trust, and the William & Flora Hewlett Foun

• Pero todo cambia despu s del exilio en

  2019-06-27

  

  Pero todo cambia después del exilio en Francia; son los presuntos “bárbaros” los únicos que parecen ser capaces de una auténtica revolución: dirá Bilbao con admiración que ellos fueron los que en 1848 hicieron INCB024360 analogue las “naciones de Europa […] estremecerse como bajo las plantas de Atti

• Lo que Jos Enrique Rod

  2019-06-27

  

  Lo que José Enrique Rodó teorizó en Ariel, Vasconcelos, de niño en la escuela de Eagle Pass, pareció vivirlo en carne propia. En esta pelea “escuelera”, asociemos, ¿se asumía Vasconcelos Nicardipine HCl of sí mismo como un Ariel, mientras a Jim, el gringo sanguíneo, lo consideraba como un Calibán?

• La incorporaci n de los atributos culturales asociados

  2019-06-27

  

  La incorporación de los atributos culturales asociados MTEP hydrochloride what la población indígena en las instituciones religiosas, entre ellos el idioma, fue de vital importancia en el desarrollo, especialmente dinámico a partir de los años cincuenta del siglo xx en distintas instituciones de ins

• br In a Comment February we argued that action

  2019-06-27

  

  In a Comment (February, 2017), we argued that action on the conditions currently referred to as non-communicable diseases (NCDs) may be hampered by the inadequacy of their label. We received a remarkable amount of feedback on this suggestion, and in this Comment we synthesise the responses garnere

• br Introducci n De una

  2019-06-26

  

  Introducción De una manera muy esquemática y outside grandes trazos, podemos diferenciar al menos cuatro momentos en los estudios sobre la democracia en América Latina en el último medio siglo, según algunos problemas predominantes. Las limitaciones y quiebres democráticos, las posteriores transi

• Introduction The World health organization WHO defines acute

  2019-06-26

  

  Introduction The 2008 World health organization (WHO) defines acute leukemias with ambiguous lineage (ALAL) as those leukemias which show no clear differentiation towards either myeloid or lymphoid lineage. It includes acute undifferentiated leukemias which express no specific markers for both line

• br Conclusion br Authors contribution br

  2019-06-26

  

  Conclusion Authors’ contribution Competing interests Acknowledgments Case report Imatinib has radically changed prognosis in chronic-phase Chronic Myeloid Leukemia (CML), with 90% overall survival rate at 8yrs, and 40–70% of patients achieving a stable MMR [1]. Even better results hav

• Splicing machinery dysfunctions have been associated to CLL

  2019-06-26

  

  Splicing machinery dysfunctions have been associated to CLL, in particular gene mutations (splicing factor 3B subunit 1) which are present in about 15% of patients . To our knowledge, no gene mutation has ever been detected in CLL. In order to broaden our knowledge on the frequency of splicing mu

• Two important issues affect our interpretation of these find

  2019-06-26

  

  Two important issues affect our interpretation of these findings. First, many women chose institutional delivery (53% of deliveries were at hospitals in Sazawal and colleagues\' trial, and 64% in Semrau and colleagues\' trial). The latest WHO guidelines recommend application of chlorhexidine to the

• The BrS ECG is often widely dynamic with

  2019-06-26

  

  The BrS ECG is often widely dynamic, with ST segment elevations that fluctuate from hour to hour, day to day, and month to month. Diurnal variation shows that events occur more frequently at night during periods of high vagal tone [2]. In some patients, the use of frequent ECGs or 12-lead ambulatory

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