• Accumulated evidence indicates that apelin

  2019-10-10

  

  Accumulated evidence indicates that apelin plays a protective role in ischemic stroke, contributing to post-stroke recovery (Yang et al., 2014; Chen et al., 2015; Xin et al., 2015; Yan et al., 2015). Apelin gene (APLN) encodes prepro-apelin with 77 amino acids, while the C-terminal 23 Palifosfamide

• br Materials and methods br Results

  2019-10-10

  

  Materials and methods Results Discussion We have evaluated the breast cancer prevention potential of PR blockade under conditions that included exposure to progestogens that are relevant to women (progesterone and MPA) and are known to differ in their receptor-binding and down-stream effect

• Our observation that nuclear but

  2019-10-10

  

  Our observation that nuclear, but not cytoplasmic EP4 expression is associated with different outcomes is interesting. In breast cancer, using the same methods, we did not detect EP4 in the nucleus of malignant PF-03814735 whereas cytoplasmic EP4 was commonly observed [13]. While G protein-coupled

• For radiochemotherapy it is well known that mitotic cell dea

  2019-10-09

  

  For radiochemotherapy, it is well known that mitotic cell death and apoptosis present the major cell death modes. More recently, autophagy-dependent cell death has been described to occur upon radiochemotherapy (Daido et al., 2005, Song et al., 2017). This form of regulated cell death depends on com

• br Materials and Methods br Author Contributions br Conflict

  2019-10-09

  

  Materials and Methods Author Contributions Conflicts of Interest Acknowledgments This work was sponsored by the National Natural Science Foundation of China (81802517), the Integrated Traditional Chinese and Western Medicine of Shanghai (ZHYY-ZXYJHZX-1-03), the Clinical Research Program

• Several studies highlighted the potential of EOCs to promote

  2019-10-09

  

  Several studies highlighted the potential of EOCs to promote adverse effects on aquatic organisms. It was reported the toxicity of BPA to invertebrates and fish, and the effect of lipophilicity on toxicity was analyzed (Mathieu-Denoncourt et al., 2016). There was reported the effects of PPCPs on aqu

• At present there have been relatively

  2019-10-09

  

  At present, there have been relatively few studies that evaluated potential correlations between pulmonary and pleura metastases, hilar and mediastinal motilin receptor nodes, and organs associated with distant metastasis and EGFR mutations [33,34,37]. Further research on these relationships is nee

• Although CCR expression clearly identifies

  2019-10-09

  

  Although CCR6 expression clearly identifies MBC precursors within the GC, we found that the expression of this chemokine receptor by responding ikk inhibitor was not required for MBC differentiation and had no detectable impact on the GC subsets analyzed in this study. Although this is in agreement

• If the effects described here are present

  2019-10-08

  

  If the effects described here are present in catalysis, their empirical confirmation poses many challenges. Cat state correlations are fragile outside an environment especially suited for their preservation. As present day observational techniques whether in vivo or in vitro were not designed bearin

• br Acknowledgements br Introduction Endothelial cells consti

  2019-10-08

  

  Acknowledgements Introduction Endothelial Pyocyanin constitute a unique source of humoral factors that may regulate the functions of other cell types via paracrine or endocrine pathways [1]. Among the many molecules originated from the endothelium, nitric oxide (NO) plays versatile roles in m

• Studies have shown that endothelial

  2019-10-08

  

  Studies have shown that endothelial cells damaged by SAH can release a large amount of ET-1, thus its plasma level is elevated and is positively correlated with the symptoms of SAH (Lei et al., 2015, Masaoka et al., 1989). Our data obtained from SAH-along rabbits were consistent with these findings.

• br Conclusions br Introduction The

  2019-10-08

  

  Conclusions Introduction The terms endocrine active and endocrine disruptive have been used to describe an ever-expanding list of naturally-occurring and synthetic compounds that interact with mammalian hormonal systems, and in particular, the reproductive system. These compounds have been ass

• Circulating NK subsets also show considerable differences in

  2019-10-08

  

  Circulating NK subsets also show considerable differences in homing molecules. CD56bright PKI 14-22 amide, myristoylated express the chemokine receptor CCR7 and L-selectin, which drive their migration to secondary lymphoid organs (Fehniger et al., 2003). In contrast, CD56dim display a high density

• thyrotropin releasing hormone br Results br Discussion Oxyst

  2019-10-08

  

  Results Discussion Oxysterols and EBI2 have received growing attention in the field of immunology, with works highlighting an important role for EBI2 in immune cell migration. However, these studies are mainly limited to animal models (Chalmin et al., 2015, Hannedouche et al., 2011, Kelly et a

• squalene epoxidase br Inhibiting APC C during

  2019-10-08

  

  Inhibiting APC/C during Interphase and prior to Anaphase Because ubiquitylation by APC/C triggers cell division, it is essential that APC/C is restrained until cells are prepared for its substrates to be degraded. In addition to regulation by phosphorylation, an additional layer of control comes

16731 records 996/1116 page Previous Next First page 上5页 9969979989991000 下5页 Last page