• Given the importance of the

  2018-10-24

  

  Given the importance of the master regulatory HOX genes for patterning during embryogenesis, we expect that the ectopic expression of a specific HOX code could allow for enhanced development of desired tissues in vitro. One example is human HOXB4, which is highly expressed in the hematopoietic stem

• A nuance of the conventional conditions has been that while

  2018-10-24

  

  A nuance of the conventional conditions has been that while overall amplification of cell number occurs in the cultures, the percentage of the population possessing regenerative capacity (i.e., SSCs) declines over a several-month period (Kanatsu-Shinohara et al., 2003, 2005, 2011; Kubota et al., 200

• SGC707 In summary we show that calreticulin and TGF

  2018-10-24

  

  In summary, we show that calreticulin and TGF-β signaling intersect downstream of TGF-β receptors I and II. The presence of calreticulin permits TGF-β-mediated inactivation of GSK3β and thus promotes SNAIL2/SLUG-regulated repression of E-cadherin. This condition is sine qua non for the expression an

• These organoid technologies have been pioneered for the smal

  2018-10-24

  

  These organoid technologies have been pioneered for the small intestine (Sato et al., 2009) and later extended also to other organs or parts of organs (Nakano et al., 2012). Recently, protocols for the generation of human brain-like organoids have been developed, including protocols for cerebral (La

• Measurements of light hadrons produced in heavy ion collisio

  2018-10-24

  

  Measurements of light hadrons produced in heavy ion collisions at RHIC energies indeed indicated the suppression of hadron production by over a factor of five in central Au+Au collisions [6]. Meanwhile, no suppression was observed for the same hadrons and high-energy direct photons in case of d+Au c

• Fig also shows the theoretical dependences

  2018-10-24

  

  Fig. 3 also shows the theoretical dependences of the axl inhibitor of the allowed transitions on the width of InGaAsSb/AlGaAsSb quantum wells at liquid nitrogen temperature. The dash-dot line 1 corresponds to the calculated energy of the transitions between the ground state of heavy holes and the f

• The first stage of the study involved assessing the

  2018-10-24

  

  The first stage of the study involved assessing the entropy increase in the training set which consisted of the data generated using the above-mentioned algorithms. Entropy was calculated by Shannon\'s formula [9]: where is the probability of selecting an AICAR from the cluster. The link between

• br Conclusion br Acknowledgements The

  2018-10-24

  

  Conclusion Acknowledgements The authors would like to thank the funders of this project, the Canadian Institute of Health Research (CIHR). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. Introduction Evidence fro

• The results also revealed several effects of beliefs

  2018-10-24

  

  The results also revealed several effects of beliefs about preventive services, as well as personal history and characteristics, on responses to messages. Participants who perceived their risk of cancer as being lower than average (OR=2.06 CI=1.33, 3.19, p Discussion The research findings presente

• As shown in Fig the proportion of the

  2018-10-24

  

  As shown in Fig. 1, the proportion of the state budget spent on health care increased by 50% from 14.1% to 21.3% over the study period. The largest part of this spending was for Medicaid and other medical benefit payments, 77% of the total in FY2014. Other significant components were for prison heal

• A number of multi purpose household surveys have

  2018-10-24

  

  A number of multi-purpose household surveys have started to acknowledge that healthcare-seeking involves more than one single healthcare provider (e.g. the Indian Human Development Survey, or the World Bank Living Standards Measurement Survey in Tanzania; Desai & Vanneman, 2016; National Bureau of S

• Yet the emphasis on the social

  2018-10-24

  

  Yet, the emphasis on the social and/or political purpose of timebanking may have obscured the fact that they are, at the core, exchange networks. TBs are created to offer a space for exchanges of services between individuals, even though the TB may encourage other activities, such as social gatherin

• Using the IPEA DATA the five macro

  2018-10-23

  

  Using the IPEA/DATA, the five macro-socioeconomic variables were: the homicide and suicide rate per 100,000 inhabitants, the percentage of poor people, the Gini index as an income inequality measurement, the open unemployment rate and government expenses. These macro-variables were disaggregated for

• There is a general consensus that immunobiology of

  2018-10-23

  

  There is a general consensus that immunobiology of HPV clearance in course of natural infection mainly relies on cell-mediated immunity (Stanley, 2006). In this context, the role of natural humoral immunity is believed to exert minor protective effects through the neutralization of functional epitop

• The method used in our study for measuring epigenetic age

  2018-10-23

  

  The method used in our study for measuring epigenetic age was based on a model trained on genome-wide DNA methylation extracted from WBC (Hannum et al., 2013). As our measurements were taken from extracted WBC, epigenetic age measured in our study could be a proxy measure for the immune response to

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