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na ca exchanger En otro caso la dilatada digresi
2019-04-23
En otro caso, la dilatada digresión filosófica de tono panteísta culmina en una Mercedes que pronuncia la palabra “cosmos”; el editor, sin duda, transforma este momento climático en una escena con cierta cursilería: Para sorprender al autor al momento de tomar la pluma y enmendarse la página de ve
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Estas ideas permanecieron vigentes durante mucho tiempo ante
2019-04-23
Estas ideas permanecieron vigentes durante mucho tiempo antes de la revolución científica desatada por el racionalismo. Un ejemplo es cómo las nociones neumáticas —derivadas de la idea de que el mundo fue creado por un soplo divino— todavía son palpables en el Primero sueño de sor Juana cuando inici
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The gallstone Lith gene map
2019-04-23
The gallstone (Lith) gene map has been updated, which lists all known genetic loci that confer gallstone susceptibility, as well as candidate genes in inbred strains of mice. Understanding molecular genetics of gallstone disease in mice will push for the identification of human Lith genes. In additi
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The study reported high rates of antimicrobial
2019-04-23
The study reported high rates of antimicrobial resistance and also reminds us of the paucity of new drugs to treat such infections, especially in neonates, as well as the paucity of data on antimicrobial pharmacokinetics in this population. Observational and interventional multicentre studies are ne
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What can be done to reduce morbidity and mortality
2019-04-23
What can be done to reduce morbidity and mortality in HEU infants? Notably, a third of all mortality in the Botswana trial occurred early, before randomisation. Similarly, in a trial of more than 14 110 infants in Zimbabwe, done in the pre-MTCT-prevention era, HIV-exposed uninfected infants had 50%
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br DNA damage and response
2019-04-23
DNA damage and response (DDR) DNA in cells of living organisms is continuously exposed to devastating factors present endogenously and exogenously which can introduce DNA damage thereby resulting in loss of genome integrity [30]. Genome integrity is affected by DNA replication errors, endogenous
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Patients with endophytic tumors had a
2019-04-23
Patients with endophytic tumors had a 2.6-fold higher rate of local recurrence than those with exophytic tumors. The 5-year local control rates were 64% and 95% in those with endophytic and exophytic lesions, respectively. The correlation of tumor morphology with local recurrence in patients with ea
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If the patient s coronary artery is
2019-04-22
If the patient’s coronary artery is very close to the ablation target site, or if the origin of the VT/VPCs cannot be estimated by only the 12-lead ECG, for example, because of a severely deformed thorax or an alteration in the morphology of the VT, the CartoSound® system can be a useful tool for as
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br Remote technologies The platforms available
2019-04-22
Remote technologies The platforms available for remote monitoring of ICDs differ. Wand-based (“inductive”) systems require patient-driven downloads relayed via telephone connections to tracking facilities [4,5]. These are becoming obsolete. This is because they demand coordination with a device c
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nimesulide Involvement of the ventricular myocardium can lea
2019-04-22
Involvement of the ventricular myocardium can lead to delayed conduction or anatomical obstacles that are labile to ventricular tachyarrhythmia. Arrhythmias are independently predictive of sudden cardiac death (SCD) [9]. SCD is common in patients with cardiac AL amyloidosis, and prophylactic implant
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br Discovery of S PR as a CBA
2019-04-22
Discovery of S1PR2 as a CBA sensor in the liver Early studies reported that activation of the ERK1/2 and AKT signaling pathways by CBAs was PTX-sensitive, suggesting a role for a Gαi-linked GPCR. To identify which GPCR activates the ERK1/2 and AKT signaling pathways, the cDNAs encoding more than
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During our analysis we sought to uncover the source of
2019-04-22
During our analysis, we sought to uncover the source of the oft-cited so-called fact that the risk of maternal mortality of women aged 15–19 years is twice that of women aged 20–24 years (and that the risk for those younger than 15 years is five-times higher). We identified dozens of instances over
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Economic sanctions have exacerbated the brutality of
2019-04-22
Economic sanctions have exacerbated the brutality of this conflict many-fold, removing any prospects for peace and reconciliation. We need some reality to gauge their manifold effects before Syria descends into another Iraq, the devastating health consequences of which were well documented. Syria u
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br Malaria is a major
2019-04-20
Malaria is a major public health problem and a leading cause of mortality worldwide, especially in sub-Saharan Africa, where 90% of the world\'s 627 000 malaria deaths occur every year. However, the disease is usually curable if diagnosed quickly. Diagnosis is often made on the basis of clinical s
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Prostaglandin E2 br Methods We reviewed http www canadiancan
2019-04-20
Methods We reviewed http://www.canadiancancertrials.ca/ and http://www.ontario.canadiancancertrials.ca/ in order to identify ongoing bone oncology-related trials. We used the keywords: bone, bone metastasis, bone treatment, cancer therapy induced bone loss and bisphosphonates for searching. We al
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