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El n mero de correspondiente al segundo semestre de
2019-06-13
El número 61 de , correspondiente al segundo semestre de 2015, ofrece seis artículos en su sección Política y Sociedad. El primero RG7204 cargo de Wilfredo Padrón Iglesias, “La masonería, un punto sombrío en la trayectoria de Francisco de Miranda”, trata sobre esta importante figura, quien es consid
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br Discussion CML was the first malignancy to be linked
2019-06-13
Discussion CML was the first malignancy to be linked to a clear genetic abnormality, the Philadelphia chromosome. This chromosomal abnormality is so named because of the city in which it was first discovered and described in 1960 by Peter Nowell and David Hungerford [1]. The fusion protein result
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Idelalisib demonstrates a dual mechanism of action by
2019-06-13
Idelalisib demonstrates a dual mechanism of action by inhibiting pro-survival signalling pathways [6], and, like other kinase inhibitors, leads to re-localisation of tumour order KU57788 by blocking ingress into and promoting egress out of the lymph node into the blood. Release from the protective
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Interpretation AMWHO is a useful
2019-06-13
Interpretation AMWHO is a useful forum for students to improve their knowledge of global health issues, and sharpen their skills in diplomacy, communication, problem solving, and conflict resolution. Emory University (Atlanta, GA, USA) will host the next national AMWHO conference in October, 2016. E
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The starting point is to address the huge gap in
2019-06-13
The starting point is to address the huge gap in surveillance capabilities identified in 2014 by the WHO\'s first global report on surveillance of antimicrobial resistance. To address this H-Lys(Ac)-OH.HCl gap, WHO\'s action plan is being implemented in phases from early 2016 onwards, gathering in
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Go 6976 br Ablation strategies from targeted to homogenizati
2019-06-12
Ablation strategies – from targeted to homogenization The techniques and principles originally developed in postinfarction scar have been translated and applied to patients with various etiologies of fibrosis and confluent scar including Chagasic cardiomyopathy, nonischemic cardiomyopathy, arrhyt
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Roughly years have gone by since the
2019-06-12
Roughly 15 years have gone by since the identification of the main characters involved in the interplay of the RANK–RANKL system. This gave rise to the race for elucidating their biological role . In those years, in vivo silencing experiments for both Receptor Activator of Nuclear Factor κ B (RANK)
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br Demographic and arrhythmia characteristics
2019-06-12
Demographic and arrhythmia characteristics: gender, circadian pattern of VF, and atrial arrhythmias The prevalence and arrhythmic risk of BS and ERS differ considerably. The BS ECG pattern occurs rarely in the general population, while the ER pattern is a common ECG phenomenon, especially in youn
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br Disclosures br Acknowledgments br Introduction Long
2019-06-12
Disclosures Acknowledgments Introduction Long-term endurance sports have recently been recognized as one of the risk factors for atrial fibrillation (AF) [1–8]; widely accepted risk factors for AF include age, hypertension, diabetes mellitus, structural nicergoline disease, hyperthyroidism
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The most compelling apparent evidence in support of the depo
2019-06-12
The most compelling apparent evidence in support of the depolarization hypothesis derives from the seminal studies of Nademanee et al. [129]. showing that radiofrequency ablation (RFA) of epicardial sites displaying late potentials and fractionated bipolar electrograms in the RVOT of patients with
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br Methods br Results Characteristics of
2019-06-12
Methods Results Characteristics of studies included in the analysis are described in the accompanying Lancet paper. We included 119 studies (58 from high-income countries and 61 from low-income and middle-income countries) in this ampk inhibitor analysis. Worldwide in 2010, an estimated 11 56
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Pepstatin A Repurposing use of approved drugs for new indica
2019-06-12
Repurposing (use of approved drugs for new indications) or repositioning (use of drugs whose development was not continued for new indications) of existing drugs has been put forward as a method to overcome some of these issues. Indeed, drug repositioning and repurposing could lead to higher rates o
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Visto el franquismo como el gran eje de la discordia
2019-06-12
Visto el franquismo como el gran eje de la discordia, el punto de in flexión se produjo en 1949 con motivo de la presentación en la onu de una propuesta conjunta de cuatro países de América Latina: Brasil, Bolivia, Colombia y Perú. La propuesta de resolución del cuatripartito latinoamericano (proyec
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br Discussion Intriguingly in a
2019-06-11
Discussion Intriguingly, in a case report about elevation of skeletal enzymes in ultramarathon runners, the CK level reached its peak value one day after the run, had a ∼4-day plateau, and began to decline after a few more days. The sustained increase of plasma CK in this athlete was quite differ
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The STAR VT trial is a randomized
2019-06-11
The STAR-VT trial is a randomized trial examining the role of ablation in patient with an indication for ICD implantation [97]. The inclusion criteria targeting 562 patients with secondary prevention indications as well as primary prevention patients with inducible VT, where nonischemic cardiomyopat
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