• A number of multi purpose household surveys have

  2018-10-24

  

  A number of multi-purpose household surveys have started to acknowledge that healthcare-seeking involves more than one single healthcare provider (e.g. the Indian Human Development Survey, or the World Bank Living Standards Measurement Survey in Tanzania; Desai & Vanneman, 2016; National Bureau of S

• Yet the emphasis on the social

  2018-10-24

  

  Yet, the emphasis on the social and/or political purpose of timebanking may have obscured the fact that they are, at the core, exchange networks. TBs are created to offer a space for exchanges of services between individuals, even though the TB may encourage other activities, such as social gatherin

• Using the IPEA DATA the five macro

  2018-10-23

  

  Using the IPEA/DATA, the five macro-socioeconomic variables were: the homicide and suicide rate per 100,000 inhabitants, the percentage of poor people, the Gini index as an income inequality measurement, the open unemployment rate and government expenses. These macro-variables were disaggregated for

• There is a general consensus that immunobiology of

  2018-10-23

  

  There is a general consensus that immunobiology of HPV clearance in course of natural infection mainly relies on cell-mediated immunity (Stanley, 2006). In this context, the role of natural humoral immunity is believed to exert minor protective effects through the neutralization of functional epitop

• The method used in our study for measuring epigenetic age

  2018-10-23

  

  The method used in our study for measuring epigenetic age was based on a model trained on genome-wide DNA methylation extracted from WBC (Hannum et al., 2013). As our measurements were taken from extracted WBC, epigenetic age measured in our study could be a proxy measure for the immune response to

• In this issue of Vranckx and colleagues

  2018-10-23

  

  In this issue of , Vranckx and colleagues show that a LEDGIN termed CX014442 specifically alters HIV-1 genomic integration in a manner that is similar to that associated with LEDGF depletion (). The authors carefully characterized HIV integration sites in the presence of various concentrations of CX

• The High Fat Diet HFD

  2018-10-23

  

  The High Fat Diet (HFD) fed mouse is a widely used model to study insulin resistance (Winzell and Ahren, 2004), and the phenotype has many of the risk factors associated with metabolic syndrome (Grundy et al., 2004). The mice are obese, and have elevated cholesterol and blood glucose. The blood Defo

• Our previous studies identified dysfunctional

  2018-10-23

  

  Our previous studies identified dysfunctional sphingolipid metabolism, due to pathological activation of ASM in diabetic retina and bone marrow, as an important metabolic insult contributing to pro-inflammatory changes in the retina and development of diabetic retinopathy (Opreanu et al., 2011; Tikh

• The vasculature is important for providing

  2018-10-23

  

  The vasculature is important for providing a neurogenic niche for stem/progenitor cells and neuroblasts in the V-SVZ under physiological (Shen et al., 2008; Tavazoie et al., 2008; Mirzadeh et al., 2008) and post-stroke (Zhang et al., 2014) conditions. In addition, vascular endothelial cells produce

• adenosine triphosphate These findings must be interpreted wi

  2018-10-23

  

  These findings must be interpreted with limitations in mind. The study was a parallel group, longitudinal design typical for assessing treatment effects. However, the control group were healthy adolescents rather than patients randomized to placebo, due to ethical concerns of withholding treatment a

• In a study published in in February

  2018-10-23

  

  In a study published in in February 2017, investigators from the Infant Brain Imaging Study (IBIS) described promising findings in screening children for autism spectrum disorders (ASDs). Using raas inhibitor magnetic resonance imaging (MRI) to assess cortical development and brain volume, investi

• Collagen I and various proteoglycans contribute

  2018-10-23

  

  Collagen I and various proteoglycans contribute to the tensile strength and viscoelastic properties of the tendon tissue, respectively (Puxkandl et al., 2002; Robinson et al., 2004). Furthermore, proteoglycans and cross-linking MK-2206 Supplier modulate collagen I fibrillogenesis during rest and tr

• One of the limitations of this study is the

  2018-10-23

  

  One of the limitations of this study is the differences in the patient populations between the two CRC patient cohorts. As shown in Table 1 and 2, there were differences in the number of patients with stage IV CRC between cohort 1 and cohort 2. At first, we validated the clinical significance of SNO

• LC MS configuration Nanoscale LC separation of the tryptic p

  2018-10-23

  

  LC-MS configuration Nanoscale LC separation of the tryptic peptides was performed with a NanoAcquity system (Waters Corporation). Samples were loaded on to a Symmetry C18 5μm, 2cm×180μm trap column (Waters) at a flow rate of 5μl/min prior to separation on a Bridged Ethyl Hybrid C18 1.7μm, 25cm×75μm

• br Discussion Genome wide analyses

  2018-10-23

  

  Discussion Genome-wide analyses of the mammalian transcriptome revealed that lncRNAs is pervasively transcribed in the genome and accumulating studies have demonstrated that lncRNAs as novel regulatory molecule plays critical roles in mammalian development [1,2], but little is known about the pot

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