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SHANK haplo insufficiency induced by heterozygous loss of f
2018-11-05
SHANK3 haplo-insufficiency induced by heterozygous loss of function mutations represents a clear model of abnormal gene dosage leading to ASD (Durand et al., 2007; Yi et al., 2016) that can be reversed by genetically re-introducing SHANK3 normal levels of expression, including during adulthood, in m
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s6 kinase br Hydrogen production by chemical looping
2018-11-05
Hydrogen production by chemical looping reforming of SWCO Results and discussion Conclusions The main conclusions that can be drawn from the present study are the following: Introduction As reported by Coetzee et al. (2007) s6 kinase mine drainage (AMD) occurs in sulphide-bearing mine w
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br Discussion The results suggest that there
2018-11-05
Discussion The results suggest that there is a significant relationship between the chronotype and the quality of sleep in the medical students evaluated, corroborating the research hypothesis. The evening-type individuals showed worse quality of sleep when compared with the morning and indiffer
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Capillary electrophoresis coupled to mass spectrometry CE
2018-11-05
Capillary electrophoresis coupled to mass spectrometry (CE–MS) is a sensitive proteomic analytical technique that is robust with high reproducibility of results in an acceptable time frame [11]. In CE–MS, capillary zone electrophoresis is interfaced with high resolution mass spectrometry; electropho
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Bedtime and wake time were not related to overweight or
2018-11-05
Bedtime and wake time were not related to overweight or obesity in our study, however an EL sleep timing behavior, corresponding to a longer duration of sleep, resulted in a better weight control compared to the others sleep timing behaviors. In a recent Australian cross-sectional study, adolescent
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br Conclusions This paper described the design of
2018-11-05
Conclusions This paper described the design of stochastic and potentiometric microsensors based on porphyrins and polymeric surfactants for the enantioanalysis of fucose in biological fluids such as whole blood. Five stochastic microsensors: ZnTSPP/DP, ZnTSPP/CP, SUV/DP, SUV/CP, SULV/DP exhibited
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Airway epithelial cells present as one of the first
2018-11-05
Airway epithelial cells, present as one of the first lines of defense for inhaled particulate matter, represent a major determinant in the interaction of a foreign body with other major body compartments. In addition, epithelial hexokinase regulation are involved with the formation and maintenance
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CX-4945 Ribosomal DNA rDNA is such a part of the genome
2018-11-03
Ribosomal DNA (rDNA) is such a part of the genome. It encodes the RNA components of ribosomes; the cellular machines responsible for making proteins. rDNA exists in 100s of copies/genome and is organised into large repetitive arrays clustered on a number of CX-4945 (). Ribosomes have often been assu
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Wnt-C59 Competencia es de inversi n e innovaci n
2018-11-03
Competencia es de inversión e innovación estratégica. En el caso de Gruma esta es la forma de competencia dominante, la empresa ha invertido en general en desarrollar su escala y capacidad productiva, así como en su diversificación. Su estrategia de expansión ha seguido una senda de: 1. Crecimiento
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br Experimental design materials and methods X ray diffracti
2018-11-03
Experimental design, materials and methods X-ray diffraction datasets were collected at synchrotron beamlines ID23-1 [2] (ESRF) and XALOC [3] (ALBA), from flash cooled (in liquid nitrogen) single crystals and kept under nitrogen gas during data collection. Diffraction data already reduced and sca
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The study had a number of limitations First individuals in
2018-11-03
The study had a number of limitations. First, individuals in the ADHD group had lower IQ than controls; however, analyses were run with and without IQ as a covariate and this did not change the results. Second, the use of sLORETA may constrain the interpretation as the images this package produces l
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Affective memory biases a key element of
2018-11-03
Affective memory biases, a key element of the cognitive (Disner et al., 2011) and neuropsychological models of MDD (Roiser and Sahakian, 2013), are a common finding (Dalgleish and Werner-Seidler, 2014; Bradley and Mathews, 1988). Dalgleish and Werner-Seidler (2014) highlight the key components of th
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br A year old man presented with an asymptomatic subcutaneou
2018-11-03
A 56-year-old man presented with an asymptomatic subcutaneous mass on the extensor side of left forearm for 2 years. On examination, a 6 cm × 10 cm, flesh-colored, rubbery–elastic, multinodular subcutaneous mass was found on the left forearm. Additionally, there were many mature hairs arising from
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br Experimental details The rolled plates of naval grade
2018-11-03
Experimental details The rolled plates of naval grade HSLA steel with thickness of 5 mm were cut to the required dimensions (100 mm × 150 mm) by abrasive cutting to prepare the joint configurations, as shown in Fig. 1(a) and (b). The chemical composition of parent metal is presented in Table 1. T
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br Experiment br Results and
2018-11-03
Experiment Results and discussion Conclusions Acknowledgments The authors thankfully acknowledge the financial support from the Defence Research and Development Organization, Ministry of Defence, Govt. of India, New Delhi in order to carry out the present study. They are grateful to Dire
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