• A potentially exciting possibility for deriving

  2018-10-20

  

  A potentially exciting possibility for deriving podocytes has been created by studies by Romagnani and co-workers, who identified and isolated renal progenitor cells (RPCs) from the parietal epithelium of Bowman\'s capsule of the adult kidney (Ronconi et al., 2009). This CD133+CD24+ cell population,

• br Acknowledgements The authors are grateful to Dr Viktor Do

  2018-10-20

  

  Acknowledgements The authors are grateful to Dr. Viktor Dombrádi (University of Debrecen) for suggestions and comments on the manuscript. The authors would like to acknowledge the excellent technical help of Iren Mezo and Maria Balogh. We thank Michael Kyba (University of Minnesota, MN, USA) for

• Taken together these findings suggest a working model

  2018-10-20

  

  Taken together, these findings suggest a working model to define CS-derived cell lineages with cardiovascular differentiation potential from the adult human heart (Figure 7E). In this model, CD90 expression segregates adult human CS-derived dexamethasone acetate with differing cardiomyogenic differ

• Functional human endothelial cells differentiated

  2018-10-20

  

  Functional human endothelial cells differentiated from hPSCs could be beneficial for many potential clinical applications (Burridge et al., 2012; Kaupisch et al., 2012; Levenberg et al., 2002; van der Meer et al., 2013), including engineering new blood vessels, endothelial cell transplantation into

• Studies from other glandular tissues

  2018-10-20

  

  Studies from other glandular tissues, like mammary gland, revealed CD24hi/CD29lo- (Shackleton et al., 2006) expressing ambroxol hydrochloride cost as potential stem cells. In mice, we reported that intraglandular transplantation of primary-sphere-derived CD24+/CD29+ cells could ameliorate radiation

• br Results br Discussion We examined

  2018-10-20

  

  Results Discussion We examined gene expression in human intestinal tissue across the developmental continuum in order to determine maturity of in-vitro-derived HIOs. Using global RNA expression data obtained by RNA-seq, several different analyses demonstrated that the HIO transcriptome closely

• br Experimental Procedures br Author Contributions

  2018-10-20

  

  Experimental Procedures Author Contributions Acknowledgments Introduction Bone marrow stromal cells (BMSCs, also called bone-marrow-derived mesenchymal stromal cells) are heterogeneous populations that likely contain varying levels of tripotent (osteogenic, adipogenic, and chondrogenic [

• br Experimental Procedures br Author Contributions

  2018-10-20

  

  Experimental Procedures Author Contributions M.C. designed, performed, and analyzed all experiments. S.Y.L. performed MO injections and WISH. W.K. conducted embryo treatments and qPCR. K.A. provided cyp24a1, cyp2r1, and cyp27 plasmids. W.G. provided guidance and edited the manuscript. T.E.N. g

• cc-5013 Supplier Introduction Oligodendrocyte progenitor cel

  2018-10-20

  

  Introduction Oligodendrocyte progenitor cc-5013 Supplier (OPCs) in the mammalian cerebral cortex have been suggested to originate from the ventral telencephalon (He et al., 2001; Marshall and Goldman, 2002). However, cell fate mapping using Emx1::Cre transgenic mice show that many oligodendrocytes

• Since the production of lactic acid seems to be the

  2018-10-20

  

  Since the production of lactic Fer-1 seems to be the cause of the genotoxic stress, modifying the culture medium could control its production and its effects. Because hESC do not metabolize carbon sources such as fructose or galactose, which generate less lactate, an option could be to use lower co

• Wnt agonist 1 Nishi et al a b have developed a method of

  2018-10-20

  

  Nishi et al. (2014a, 2014b) have developed a method of inducing cancer stem-like Wnt agonist 1 (CSCs) through the reprogramming and partial differentiation of the immortalized but otherwise normal MCF10A human mammary epithelial cell line. To experimentally test our computational model of oncometabo

• br Results br Discussion The adult kidney has a low

  2018-10-20

  

  Results Discussion The adult kidney has a low rate of homeostatic cell cycling; yet, following injury, even one severe enough to cause total renal failure, widespread cell proliferation and functional recovery can occur. The mechanisms responsible for generation of new kidney apoptosis during

• br Experimental Procedures br Author Contributions br Acknow

  2018-10-20

  

  Experimental Procedures Author Contributions Acknowledgments We thank Abhishek Sinha, Chandan Kadur, James Ankrum, and Mamta Jain for helpful and enlightening discussions. Funding supported by the Indo-US Science and Technology Forum (IUSSTF) to J.M.K. and M.S.I.; JNCASR grant to M.S.I.; an

• miRNAs are known to regulate the expression

  2018-10-20

  

  miRNAs are known to regulate the expression of multiple targets via binding to 3′ UTR. Our finding that the miR-29 family regulates global DNA methylation and demethylation adds another role to the list of common regulatory roles of miRNAs. The miR-29 family was known to regulate ECM proteins in phy

• br Experimental Procedures br Author Contributions br Acknow

  2018-10-20

  

  Experimental Procedures Author Contributions Acknowledgments Introduction Tissue engineering technology has become one of the most promising therapeutic approaches for bone regeneration in bone defects (Zou et al., 2011; Ye et al., 2011; Xiao et al., 2011). As a source of mesenchymal ste

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