Archives
- 2018-07
- 2018-10
- 2018-11
- 2019-04
- 2019-05
- 2019-06
- 2019-07
- 2019-08
- 2019-09
- 2019-10
- 2019-11
- 2019-12
- 2020-01
- 2020-02
- 2020-03
- 2020-04
- 2020-05
- 2020-06
- 2020-07
- 2020-08
- 2020-09
- 2020-10
- 2020-11
- 2020-12
- 2021-01
- 2021-02
- 2021-03
- 2021-04
- 2021-05
- 2021-06
- 2021-07
- 2021-08
- 2021-09
- 2021-10
- 2021-11
- 2021-12
- 2022-01
- 2022-02
- 2022-03
- 2022-04
- 2022-05
- 2022-06
- 2022-07
- 2022-08
- 2022-09
- 2022-10
- 2022-11
- 2022-12
- 2023-01
- 2023-02
- 2023-03
- 2023-04
- 2023-05
- 2023-06
- 2023-07
- 2023-08
- 2023-09
- 2023-10
- 2023-11
- 2023-12
- 2024-01
- 2024-02
- 2024-03
- 2024-04
- 2024-05
- 2024-06
- 2024-07
- 2024-08
- 2024-09
- 2024-10
-
In this context it is interesting to
2018-10-30
In this context, it is interesting to note that the impact of the cellular response associated with the β-catenin co-factor BCL9/9L may be context-dependent. Indeed, in the mouse, ablation of Bcl9/9l in the intestinal epithelium abrogates the expression of genes related to epithelial–mesenchymal tra
-
The low levels of research investment for syphilis
2018-10-30
The low levels of research investment for syphilis and gonorrhoea remain (Head et al., 2013, 2015b), both in terms of total funding but also when compared to disease burden. Given the increasing levels of GSK503 in strains of Neisseria gonorrhoeae, and the continuing high burden of both these other
-
Tasquinimod br Glutaminase Inhibition Among JAK V F
2018-10-30
Glutaminase Inhibition Among JAK2 V617F-mutant Tasquinimod in vitro, as compared with their wild-type counterparts, there has been the observation of increased oxygen consumption, increased extracellular acidification, increased glutamine metabolism, and upregulated glutaminase (Zhan et al., 2015
-
br Declaration of Interests br Authorship
2018-10-30
Declaration of Interests Authorship Acknowledgments Introduction The main clinical problems of people living with HIV (PLWH) in areas with adequate healthcare standards and continued antiretroviral therapy (ART) supply are increasingly related to premature aging (Paiardini and Müller-Tru
-
br Subjects and Methods br Results br Discussion HnRNP A
2018-10-30
Subjects and Methods Results Discussion HnRNP A1 has been reported as an important autoantigen of the autoimmune response in rheumatic diseases in many articles. Autoantibodies to hnRNP complex have been detected in patients with RA, SLE and mixed connective tissue disease in succession (so
-
br The Role of Glucose Metabolism in HIV
2018-10-30
The Role of Glucose Metabolism in HIV Pathogenesis Metabolic Regulation of Monocytes Monocytes dramatically change their metabolic phenotype from oxidative to glycolytic metabolism when activated in humans (Dietl et al., 2010; Cramer et al., 2003), similar to what is observed in T cells. In a
-
br Skin and Hair Aging
2018-10-30
Skin and Hair Aging, Lifestyle and the Skin and Scalp Microbiomes William W. Mohn (Vancouver, Canada) reported on a cross-sectional study investigating the skin and scalp microbiome in relation to skin and hair aging and lifestyle, and involving 495 subjects 10–78years of age. Diversity of the sc
-
br Materials and Methods br Results br Discussion Although
2018-10-30
Materials and Methods Results Discussion Although aberrant glycosylation is common in cancer and has been linked to PCa progression (Munkley et al., 2016), our understanding of what drives these cancer associated glycan changes has been scant and has relied upon anecdotal observations. Here
-
The following is the supplementary data related to this arti
2018-10-30
The following is the supplementary data related to this article. Authors\' Contributions Conflicts of Interests Acknowledgements This work was sponsored by the National Natural Science Foundation of China (81570603), the New-100 talent Plan of Shanghai Jiao Tong University School of Medici
-
Finally we found that macroscopic analysis of whole
2018-10-30
Finally, we found that macroscopic analysis of whole tumours could predict response, and baseline Ktrans was the strongest predictor, which suggests VEGF is main determinant of vascular leakiness, though not necessarily angiogenesis. Although baseline gene expression did not strongly correlate with
-
Furthermore there are no studies exploring if additional
2018-10-29
Furthermore, there are no studies exploring if additional anti-anaerobic therapy improves DFI outcome, and in this study, we find no correlation between the high relative abundance of obligate anaerobes and a greater tendency to fail antimicrobial therapy. The decision to use targeted antimicrobials
-
For HCC the second leading cause of
2018-10-29
For HCC, the second leading cause of cancer death worldwide, there is a lack of effective drugs. The only approved drug, sorafenib, has modest survival benefits (Llovet et al., 2008; Abou-Alfa et al., 2006; Cheng et al., 2009). Immunotherapy has been considered as an effective approach for cancer tr
-
br Microorganism cultivation and secretome extraction
2018-10-29
Microorganism cultivation and secretome extraction The fungal isolates belonging to Aspergillus sp. isolated, identified and labeled as A. fumigatus LF9 was used in this study [3]. DNA sequence of this isolate is available in GenBank under accession no. JF815073. A. fumigatus LF9 was cultivated a
-
The second characteristic of the
2018-10-29
The second characteristic of the present method includes using the rate constant (k) of a first-order reaction equation with correction factor to determine catalase activity. The rate constant of a first-order reaction (k) is used to determine catalase activity due to the abnormal kinetics of catala
-
We examined fcMRI network changes between and months of
2018-10-29
We examined fcMRI network changes between 6 and 12 months of age in 92 infants of whom 36 infants had both 6 and 12 month scans (128 total datasets). The current fMRI data preprocessing strategy incorporates several recent advances that minimize the impact of head motion artifact more effectively th
15511 records 1024/1035 page Previous Next First page 上5页 10211022102310241025 下5页 Last page