Archives
- 2018-07
- 2018-10
- 2018-11
- 2019-04
- 2019-05
- 2019-06
- 2019-07
- 2019-08
- 2019-09
- 2019-10
- 2019-11
- 2019-12
- 2020-01
- 2020-02
- 2020-03
- 2020-04
- 2020-05
- 2020-06
- 2020-07
- 2020-08
- 2020-09
- 2020-10
- 2020-11
- 2020-12
- 2021-01
- 2021-02
- 2021-03
- 2021-04
- 2021-05
- 2021-06
- 2021-07
- 2021-08
- 2021-09
- 2021-10
- 2021-11
- 2021-12
- 2022-01
- 2022-02
- 2022-03
- 2022-04
- 2022-05
- 2022-06
- 2022-07
- 2022-08
- 2022-09
- 2022-10
- 2022-11
- 2022-12
- 2023-01
- 2023-02
- 2023-03
- 2023-04
- 2023-05
- 2023-06
- 2023-07
- 2023-08
- 2023-09
- 2023-10
- 2023-11
- 2023-12
- 2024-01
- 2024-02
- 2024-03
- 2024-04
- 2024-05
- 2024-06
- 2024-07
- 2024-08
- 2024-09
-
Perhaps cell cycle differences between primate and
2018-11-08
Perhaps chk1 differences between primate and rodent pluripotent stem cells preclude primate ESCs from participation in development after implantation. The time course of development also differs significantly between rodents and primates. Blastocysts develop in mice within 3.5–4days, whereas human b
-
An ever increasing number of reports have
2018-11-08
An ever-increasing number of reports have demonstrated that in animal subjects, BMMCs improve functional outcome after ischemia (Baker et al., 2007; Brenneman et al., 2010; Giraldi-Guimaraes et al., 2009; Iihoshi et al., 2004; Kamiya et al., 2008). More recently, these cells have also been evaluated
-
br Conclusions The results of this study are
2018-11-08
Conclusions The results of this study are significant for a deeper understanding of the cellular changes that take place during ex vivo expansion of BMSCs and ASCs, and appear to concur with current knowledge on the use of hypoxic environments and the occurrence of replicative senescence. Relevan
-
One limitation of using iPSCs is the
2018-11-08
One limitation of using iPSCs is the inability to carry out studies under genetically defined conditions, leading to increased experimental variability. To overcome these obstacles, we used a zinc-finger-nuclease (ZFN)-mediated gene-editing technique (An et al., 2012; Corti et al., 2012; Li et al.,
-
Both Brat and Mei P belong to the Trim NHL
2018-11-08
Both Brat and Mei-P26 belong to the Trim-NHL family of proteins, which have conserved functions in stem cell lineages from C. elegans to mouse (for review, see Wulczyn et al., 2010). Proteins within this family are potential E3 ubiquitin ligases and can act by either activating or antagonizing the m
-
Importantly we show that exogenous PAX expression
2018-11-08
Importantly, we show that exogenous PAX7 expression in these CDM cultures enables efficient myogenic progenitor propagation in vitro and in vivo regenerative potential. In addition, due to the presence of a reporter system (PAX7-ires-RFP), PAX7 expression allows purification of myogenic progenitors,
-
br Introduction Genome wide exome
2018-11-08
Introduction Genome-wide exome sequencing of microcephaly (MCPH) patients identified wd40-repeat protein 62 (wdr62) as the second most commonly mutated gene (Bilguvar et al., 2010; Nicholas et al., 2010; Yu et al., 2010). WDR62 is a ubiquitously expressed cytoplasmic protein in interphase and loc
-
br Conclusions and future perspectives Due to
2018-11-08
Conclusions and future perspectives Due to the extraordinary speed that stem cell research is proceeding, scientists rarely have time to improve or replace assay systems that are working. For industrial and clinical applications the differentiation potential assessed by in vitro differentiation w
-
I-BET-762 Supplier Respiratory chain complexes are organized
2018-11-08
Respiratory chain complexes are organized into higher oligomeric structures called supercomplexes or respirasomes. In mammalian cells, complex I (NADH:ubiquinone oxidoreductase) is associated with dimeric complex III (ubiquinol:cytochrome c oxidoreductase) and multiple copies of complex IV (cytochro
-
We found seven published clinical
2018-11-08
We found seven published clinical trials studying the effects of MSC transplantation in patients with liver cirrhosis (listed in Table 2). A pilot phase 1 study published in 2007 included four patients with decompensated liver cirrhosis (Mohamadnejad et al., 2007). Cells were derived from iliac cres
-
An important concern regarding stem cell based therapies is
2018-11-08
An important concern regarding stem cell based therapies is the potential for unwanted cell growth. In a previous study we showed that the TheraCyte encapsulation device is durable enough to withstand freezing without evidence of cell escape, suggesting that once buy Lomefloxacin HCl are sealed in
-
One attractive strategy to improve outcome in heart failure
2018-11-08
One attractive strategy to improve outcome in heart failure is to regenerate damaged myocardium by making more functional cardiomyocytes. Extensive work over the past two decades has overturned the prevailing dogma that adult cardiomyocytes do not undergo cell division by demonstrating that adult ca
-
br Materials and methods br Results br
2018-11-08
Materials and methods Results Discussion riPSCs are typically generated and cultured on MEF feeders (Liu et al., 2008). Feeders are sufficient to support rhesus iPSC long-term maintenance. However, this approach is too labor intensive for large-scale culture. Optimization of this culture sy
-
In the present study we tested five different pharmacologica
2018-11-08
In the present study, we tested five different pharmacological agents that are commonly used as selective inhibitors of Nodal/Activin signaling, namely SB431542, LY364947, A-83-01, SB505124, and SB525334 (Inman et al., 2002; Callahan et al., 2002; Laping et al., 2002; DaCosta Byfield et al., 2004; L
-
br Conclusion Human BMSCs are a promising cell
2018-11-08
Conclusion Human BMSCs are a promising cell type for regenerative medicine and tissue-engineering applications. They have the capacity for self-renewal and exhibit multipotent differentiation potential through which they can produce lineages such as osteoblasts, chondrocytes, and adipocytes (Char
15301 records 1000/1021 page Previous Next First page 上5页 9969979989991000 下5页 Last page